Pizotifen

Dosage ; Prophylaxis of vascular headache e.g. migraine; 1.5mg nocte

or 0.5mg TID (max, 4.5mg daily).

Children; up to 1.5 mg daily in divided doses.

Appetite stimulant: Children: increase the doseg

radually to around 0.025mg / kg.

Adults: Initial dose 0.5mg per day (to 0.5mg TID).

Mood elevation in elderly:

Initial dose 0.5mg daily, increased by 0.5mg per day up to 2-3 daily in divided doses.

Mode Of Action

Cyproheptadine is an antihistamine (H1) and serotonin antagonist that stimulates appetite and weight gain. L-carnitine is necessary for normal mammalian fat utilization and energy metabolism. L-Carnitine also stimulates GI and pancreatic secretions. L-lysine is important for protein synthesis.

Drug Indication emesis
Precautions Narrow angle glaucoma or urinary retention; pregnancy; activities requiring great attention like driving and operating machines.
Side Effects Sedation; rarely constipation; dry mouth; dizziness; nervousness in children.
Dosage Prophylaxis of vascular headache e.g. migraine; 1.5mg nocte or 0.5mg TID (max, 4.5mg daily). Children; up to 1.5 mg daily in divided doses. Appetite stimulant: Children: increase the dose gradually to around 0.025mg / kg. Adults: Initial dose 0.5mg per day (to 0.5mg TID). Mood elevation in elderly: Initial dose 0.5mg daily, increased by 0.5mg per day up to 2-3 daily in divided doses.
Pregnancy Category Category B1
Pregnancy Category Description Drugs which have been taken by only a small number of pregnant women and women of child-bearing age with no any established rise in the frequency of malformations or other direct or indirect detrimental effects on the foetus having been noted. Studies in animals have not shown evidence of an increased occurrence of foetal damage.