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Esomeprazole

Dosage ;

GERD without erosive esophagitis: 20 mg PO qD x 4 weeks, 20-40 mg qD IV up to 10 days, switch to PO once patient able to swallow.

GERD with erosive esophagitis: Treatment: 20mg or 40 mg PO qD x4-8 weeks.

Maint: 20 mg PO qD up to 6 months, 20-40 mg qD IV up to 10 days, switch to PO once patient able to swallow.

H. pylori eradication: Indicated for combination therapy

(with amoxicillin and clarithromycin) to eradicate H. pylori in patients with duodenal ulcer 40 mg PO qD x 10 days, WITH amoxicillin 1000 mg PO BID, AND clarithromycin 500 mg PO BID x 10 days.

Risk reduction of NSAID-associated gastric ulcer, 20-40 mg PO qD x up to 6 months. Zollinger-Ellison Syndrome, 60 mg PO qD (initial) up to 100 mg PO qD,

OR 60 mg PO BID.