Famotidine

Famotidine Brands

Brand Name	Manufacturer Name	Distributor	Drug Strength	Packaging	Formulation	Formulation Strength	Price
Acipep	kopran Ltd.	Surgilinks Ltd.	40mg	100	Tablet	per tablet	KES 600
Famotidine	Teva Pharmaceuticals	Kulal International Ltd.	40mg	30	Tablet	per tablet	KES 140
Famotidine	Teva Pharmaceuticals	Kulal International Ltd.	20mg	20	Tablet	per tablet	KES 266
Yamadin	Beximco Pharma	Madawa Pharmaceuticals Ltd.	20mg	100	Tablet	per tablet	KES 816
Yamadin	Beximco Pharma	Madawa Pharmaceuticals Ltd.	40mg	100	Tablet	per tablet	KES 1,594

Famotidine More info
Mode Of Action	Histamine H2-receptor antagonist
Drug Indication	Benign gastric and duodenal ulcers treatment, Reflux oesophagitis, Zollinger-Ellison syndrome
Precautions	Severe hepatic impairment, breastfeeding, may mask symptoms of gastric cancer, contains acid-labile granules - do not chew or crush, take 1 hr before meals
Side Effects	Masking of symptoms of gastric cancer, reversible gynaecomastia, alopecia, hepatic disorders, confusional states, galactorrhoea, blood disorders, loss of libido, acute pancreatitis, GI disturbances, skin rashes, cardiac arrhythmias, hypotension, muscular pain, nephritis, hallucinations
Special Information	It does not inhibit hepatic drug metabolism like cimetidine
Pregnancy Category	Category B1
Pregnancy Category Description	Drugs which have been taken by only a small number of pregnant women and women of child-bearing age with no any established rise in the frequency of malformations or other direct or indirect detrimental effects on the foetus having been noted. Studies in animals have not shown evidence of an increased occurrence of foetal damage.
Drug Category	DRUGS ACTING ON ALIMENTARY SYSTEM
Drug Sub-Category	H-Antagonists Dosing: Adult Duodenal ulcer: Oral: Acute therapy: 40 mg/day at bedtime (or 20 mg twice daily) for 4-8 weeks; maintenance therapy: 20 mg/day at bedtime Gastric ulcer: Oral: Acute therapy: 40 mg/day at bedtime Hypersecretory conditions: Oral: Initial: 20 mg every 6 hours, may increase in increments up to 160 mg every 6 hours GERD: Oral: 20 mg twice daily for 6 weeks Esophagitis and accompanying symptoms due to GERD: Oral: 20 mg or 40 mg twice daily for up to 12 weeks Peptic ulcer disease: Eradication of Helicobacter pylori (unlabeled use): Oral: 40 mg once daily; requires combination therapy with antibiotics Patients unable to take oral medication: I.V.: 20 mg every 12 hours Heartburn, indigestion, sour stomach: OTC labeling: Oral: 10-20 mg every 12 hours; dose may be taken 15-60 minutes before eating foods known to cause heartburn Dosing: Pediatric (For additional information see "Famotidine: Pediatric drug information") Treatment duration and dose should be individualized Peptic ulcer: 1-16 years: Oral: 0.5 mg/kg/day at bedtime or divided twice daily (maximum dose: 40 mg/day); doses of up to 1 mg/kg/day have been used in clinical studies I.V.: 0.25 mg/kg every 12 hours (maximum dose: 40 mg/day); doses of up to 0.5 mg/kg have been used in clinical studies GERD: Oral: <3 months: 0.5 mg/kg once daily 3-12 months: 0.5 mg/kg twice daily 1-16 years: 1 mg/kg/day divided twice daily (maximum dose: 40 mg twice daily); doses of up to 2 mg/kg/day have been used in clinical studies Heartburn, indigestion, sour stomach: OTC labeling: Oral: Children ≥12 years: Refer to adult dosing. Dosing: Geriatric Refer to adult dosing. Dosing: Renal Impairment Clcr <50 mL/minute: Manufacturer recommendation: Administer 50% of dose or increase the dosing interval to every 36-48 hours (to limit potential CNS adverse effects)