Dosage ; Oral dose: 50mg-200mg daily in divided doses.
Rectal dose: 100mg nocte and morning when required.
Dizziness may affect performance of skilled tasks (e.g. driving).
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Cindomet | Dawa Limited | Dawa Limited | 25mg | 100 | Capsule | per capsule | KES 60 |
| Cindomet | Dawa Limited | Dawa Limited | 25mg | 1000 | Capsule | per capsule | KES 400.00 |
| Dometin | Cosmos Limited. | Cosmos Limited | 25mg | 100 | Capsule | per capsule | KES 200.00 |
| Caredomet | Syner-Medica (K) Ltd | Syner-Medica (K) Ltd | 25mg | 1000 | Capsule | per capsule | KES 400.00 |
| Indosha | nisel | 25mg | 1000s | Capsule | Per Capsule | KES 350.00 |
| Indomethacin more info | |
|---|---|
| Mode Of Action | Inhibitors of cyclo-oxygenase (COX-1 and COX-2) enzyme that catalyzes the conversion of arachidonic acid to PGH2 e.g. Aspirin |
| Drug Indication | Acute gout, rheumatic arthritis, osteoarthritis, ankylosing spondylitis, musculo-skeletal disorders. |
| Precautions | Asthma, bronchospasm, renal disorders, elderly, may mask signs and symptoms of infections. |
| Contra-Indications | Psychiatric disorders, bleeding disorders, asthma, parkinsonism, epileptic, hepatic and renal impairment, pregnancy and lactation. |
| Side Effects | Headache, dizziness, vertigo, GI disturbances, blood dyscrasia, upper GI ulceration, hepatitis and jaundice, mental confusion and bronchospasm. |
| Dosage | Oral dose: 50mg-200mg daily in divided doses. Rectal dose: 100mg nocte and morning when required. Dizziness may affect performance of skilled tasks (e.g. driving). |
| Pregnancy Category | Category C |
| Pregnancy Category Description | Drugs which, owing to their pharmacological effects, or may be suspected of causing detrimental effects on human foetus or neonates without causing malfunctions. These effects may be reversible |
| Drug Category | DRUGS ACTING ON CNS |
| Drug Sub-Category | Drugs for treatment of gout |