Dosage ; IM 20mg QID, Oral; 30 - 60 mgTID
Not recommended to children under 12 yrs. Geriatric age not exceed 30 mg.
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Acupam | biocodex | 20mg | 5s | inj | per vial | KES 730 |
| Nefopam more info | |
|---|---|
| Mode Of Action | Not fully understood. theory is by inhibition of serotonin, dopamine, norepinephrine reuptake |
| Drug Indication | Mild to moderate pain, antipyretic, fibrositis, osteoarthritis, rheumatic spondylitis, ankylosing spondylitis. |
| Precautions | Risk of urinary retaintion, renal/hepatic/cardiac disorders, |
| Contra-Indications | history of convulsion, patient on MAOIs. |
| Side Effects | urine retaintion, blurred vision, drowsiness, hypotension, syncope, palpitation. |
| Dosage | Adult: 500mg- 1g OD or BD. Gout 750mg initially then 250mg TID. Musculoskeletal disorders: 250mg TID or QID PRN (max 1250mg daily after the first day). Children 5-16 years: 10mg/kg body weight in two divided doses |
| Pregnancy Category | Category C |
| Pregnancy Category Description | Drugs which, owing to their pharmacological effects, or may be suspected of causing detrimental effects on human foetus or neonates without causing malfunctions. These effects may be reversible |
| Drug Category | DRUGS ACTING ON CNS |
| Drug Sub-Category | Analgesics, & NSAIDS |