Dosage ; Arthritis and post-operative pain: 20mg OD (40mg may be given for the first 2 days). Dysmenorrhoea: 40mg daily for 2 days then 20mg daily 1-3 days.
Gout: 40mg stat, then 40mg daily for 4-6 days. Acute musculo-skeletal disorders:
40mg daily for 2 days then 20mg OD for 7-14 days.
Juvenile arthritis: Daily as a single dose, 15kg-5mg/kg, 16-25kg -10mg/kg, 26-45kg-15mg/kg,
over 46kg- 20mg/kg.
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Feldene | Pfizer Global Pharmaceuticals | Surgipharm Ltd | 20mg | 10 | Capsule | per capsule | KES 726.00 |
| Feldene | Pfizer Global Pharmaceuticals | Surgipharm Ltd | 20mg | 3 | Injection | per ml | KES 663.00 |
| Pirocam | Laboratory & Allied Ltd. | Laboratory & Allied Ltd | 20mg | 100 | Capsule | per capsule | KES 85 |
| Pirocam | Laboratory & Allied Ltd. | Laboratory & Allied Ltd | 20mg | 100 | Capsule | per capsule | KES 90 |
| Caroxicam | Syner-Medica (K) Ltd | Syner-Medica (K) Ltd | 20mg | 100 | Capsule | per capsule | KES 60.00 |
| Pirocam | Flamingo Pharmaceuticals Ltd. | Harley's Limited | 20mg | 100 | Capsule | per capsule | KES 55.00 |
| Roxicam | Biodeal Laboratories Ltd. | Biodeal Laboratories Ltd. | 20mg | 100 | Capsule | per capsule | KES 90.00 |
| Piroxicam more info | |
|---|---|
| Mode Of Action | Inhibitors of cyclo-oxygenase (COX-1 and COX-2) enzyme that catalyzes the conversion of arachidonic acid to PGH2 e.g. Aspirin |
| Drug Indication | Arthritis and post-operative pain; dysmenorrhoea; gout;Acute musculo-skeletal disorders; Juvenile arthritis |
| Precautions | Renal/hepatic impairment, coumarin anticoagulants, GI disturbances history. |
| Contra-Indications | Pregnancy and lactation, active peptic ulceration, porphyria, hepatic impairment. Safety in children has not been established, patient sensitive to NSAIDs. |
| Side Effects | GI disturbances, tinnitus, hearing impairment, allergic reactions, visual disturbances, alopecia, onycholysis, pancreatitis, blood dyscrasia, epistaxis, and photosensitivity. |
| Dosage | Arthritis and post-operative pain: 20mg OD (40mg may be given for the first 2 days). Dysmenorrhoea: 40mg daily for 2 days then 20mg daily 1-3 days. Gout: 40mg stat, then 40mg daily for 4-6 days. Acute musculo-skeletal disorders: 40mg daily for 2 days then 20mg OD for 7-14 days. Juvenile arthritis: Daily as a single dose, 15kg-5mg/kg, 16-25kg -10mg/kg, 26-45kg-15mg/kg, over 46kg- 20mg/kg. |
| Pregnancy Category | Category C |
| Pregnancy Category Description | Drugs which, owing to their pharmacological effects, or may be suspected of causing detrimental effects on human foetus or neonates without causing malfunctions. These effects may be reversible |
| Drug Category | DRUGS ACTING ON CNS |
| Drug Sub-Category | Drugs for treatment of gout |