Combinations ; See Below
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Ltd. | Ltd | mg | 30 | Tablet | per tablet | KES | |
| Pentamidine Isethionate More info | |
|---|---|
| Mode Of Action | It is thought to interfere with nuclear metabolism producing inhibition of the synthesis of DNA, RNA, phospholipids and proteins. |
| Drug Indication | Pneumocystis carinii pneumonia (PCP); Prevention of PCP in high-risk HIV-infected patients; trypanosomiasis and visceral leishmaniasis |
| Precautions | Use of aerosol in asthma |
| Contra-Indications | History of allergic reaction to the drug |
| Side Effects | Severe reactions due to hypotension, hypoglycaemia, arrythmias and pancreatitis |
| Dosage | Pneumocystitis carinii: I.V infusion 4mg/kg daily for at least 14 days. Visceral leishmaniasis (kala-azar): deep I.M 3-4mg 1-2weekly until the condition resolves. Trypanosomiasis; Deep I.M or I.V infusion 4mg/kg daily or on alternate days (total 7-10 injections) |
| Special Information | It is an aromatic diamidine derivative structurally similar to procainamide, amiloride and trimethoprim. |
| Pregnancy Category | Category C |
| Pregnancy Category Description | Drugs which, owing to their pharmacological effects, or may be suspected of causing detrimental effects on human foetus or neonates without causing malfunctions. These effects may be reversible |
| Drug Category | DRUGS ACTING ON INFECTIONS |
| Drug Sub-Category | Other Anti-Infective |