Dosage;
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Rorox | Tablets India Ltd. | Harley's Limited | 150mg | 10 | Tablet | per tablet | KES 315.00 |
| Roxibid | Cadila Pharmaceuticals Ltd. | Cadila Pharmaceuticals (EA) | 150mg | 10 | Tablet | per tablet | KES 350.00 |
| Roxid | Alembic Products Ltd | Europa Healthcare Ltd. | 150mg | 10 | Tablet | per tablet | KES 700.00 |
| Roxid | Alembic Products Ltd | Europa Healthcare Ltd. | 300mg | 10 | Tablet | per tablet | KES 1,160.00 |
| Roxid | Alembic Products Ltd | Europa Healthcare Ltd. | 50mg | 60ml | Syrup | per 5ML | KES 265.00 |
| Resprox | Lark | 50mg | 5ml | Syp | per 5ml | KES 90 | |
| Throx | Alkem | 150mg | 50s | Tablet | per tablet | KES 1575 |
| Mode Of Action | binds to 50s sub-unit of the bacterial ribosome and inhibits bacterial protein synthesis by preventing attachment of aminoacyl transfer RNA to its acceptor site on the ribosome. This prevents peptide bond formation by peptidyl transferase. |
|---|---|
| Drug Indication | E.N.T infections (mild to moderate), skin and soft tissues infections, gut infections. |
| Precautions | Renal and hepatic insufficiency. |
| Contra-Indications | Concommitant administration with vasoconstrictor ergot derivatives. |
| Side Effects | GI disturbances, allergic skin reactions, increased hepatic enzymes and bilirubin. |
| Dosage | Adults: 150mg BD or 300mg OD. Children: 2-5years; 5mg/kg BD. Taken on an empty stomach. |
| Pregnancy Category | Category B1 |
| Pregnancy Category Description | Drugs which have been taken by only a small number of pregnant women and women of child-bearing age with no any established rise in the frequency of malformations or other direct or indirect detrimental effects on the foetus having been noted. Studies in animals have not shown evidence of an increased occurrence of foetal damage. |
| Drug Category | DRUGS ACTING ON INFECTIONS |
| Drug Sub-Category | Macrolides |