Dosage;
Trichomonas vaginalis: 2g stat. Acute amoebiasis, symptomatic (histolytica form): Adults; 2g stat, children; 30mg/kg stat.
Asymptomatic amoebiasis: same daily dose for 3 days.
Hepatic amoebiasis, adult: 1.5g daily in one or several doses for 5 days,
Children; 30mg/kg /day in one or several divided doses for 5 days. (All doses taken at the beginning of a meal)
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Agisec | Agio Pharmaceuticals Limited | Pharma Specialities Ltd. | 1g | 2 | Tablet | per tablet | KES 54.00 |
| Cipazol Forte | Cipla Ltd. | Surgipharm Ltd | 1g | 2 | Tablet | per tablet | KES 237.00 |
| Dawasec | Dawa Limited | Dawa Limited | 1g | 2 | Tablet | per tablet | KES 40.00 |
| Dysen Forte | Nabiqasim Industries (Pvt) Ltd | Harley's Limited | 1g | 2 | Tablet | per tablet | KES 27.00 |
| Entosec | Cipla Ltd. | Surgipharm Ltd | 1g | 2 | Tablet | per tablet | KES 65.00 |
| Labgentil | Laboratory & Allied Ltd. | Laboratory & Allied Ltd | 500mg | 4 | Tablet | per tablet | KES 32.00 |
| Flagentyl | Sanofi Aventis | Laborex Kenya Eurapharma Ltd | 500mg | 4 | Tablet | per tablet | KES 310.00 |
| Olmol Forte | Intas Pharmaceuticals Ltd | Medisel Kenya Ltd | 1g | 2 | Tablet | per tablet | KES 40.00 |
| Secnid DS | Square Pharmaceuticals Ltd | ACE Pharmaceuticals Ltd | 1g | 100 | Tablet | per tablet | KES 1,800.00 |
| Secnid DS | Square Pharmaceuticals Ltd | ACE Pharmaceuticals Ltd | 500mg | 10ml | Suspension | per 5ML | KES 100.00 |
| Seczol DS | Intas Pharmaceuticals Ltd | Medisel Kenya Ltd | 1g | 2 | Tablet | per tablet | KES 83.00 |
| Secnefil | Fourts PVT Ltd. | Sai Pharmaceuticals Ltd. | 1g | 2 | Tablet | per tablet | KES 50.00 |
| Secnefil | Beta Healthcare International Ltd | Beta Healthcare International Ltd | 1g | 2 | Tablet | per tablet | KES 58.65 |
| Secnida Forte | Biopharma Laboratories Ltd. | Maxim Pharmaceuticals Ltd | 1g | 2 | Tablet | per tablet | KES 48.00 |
| Senidal | Global Pharma Healthcare Pvt. Ltd | Medox Pharmaceuticals Ltd. | 1g | 4 | Tablet | per tablet | KES 225.00 |
| Senidol | Prism Life Sciences | Galaxy Pharmaceuticals Ltd | 1g | 2 | Tablet | per tablet | KES 33.00 |
| Seole | Questa Care Inc. | Simba Pharmaceutical Ltd. | 1g | 2 | Tablet | per tablet | KES 54.50 |
| Unigentyl | Universal Pharmaceuticals Ltd. | Saicare Enterprises Ltd. | 500mg | 4 | Tablet | per tablet | KES 37.00 |
| Secnidazole | |
|---|---|
| Mode Of Action | Metronidazole is selective for anaerobic bacteria due to their ability to intracellularly reduce metronidazole to its which covalently binds to DNA, disrupt its helical structure, inhibiting bacterial nucleic acid synthesis |
| Drug Indication | Invasive intestinal amoebiasis, Giardiasis, Urogenital trichmoniasis, Acute dental infections. Surgical prophylaxis, leg ulcer and pressure sore, bacterial vaginosis, acute ulcerative gingivitis. |
| Precautions | Avoid alcohol |
| Contra-Indications | Pregnancy and lactation, blood dyscrasia, CNS disturbances. |
| Side Effects | Metallic taste, gastralgia, nausea, abdominal pain, vomiting, stomatitis. Rarely, vertigo, moderate neurological disorders. |
| Dosage | Trichomonas vaginalis: 2g stat. Acute amoebiasis, symptomatic (histolytica form): Adults; 2g stat, children; 30mg/kg stat. Asymptomatic amoebiasis: same daily dose for 3 days. Hepatic amoebiasis, adult: 1.5g daily in one or several doses for 5 days, children; 30mg/kg /day in one or several divided doses for 5 days. (All doses taken at the beginning of a meal) |
| Drug Category | DRUGS ACTING ON INFECTIONS |
| Drug Sub-Category | Anti-Amoebics |