Dosage;
100mg STAT then 50mg BD x 5 - 14 days
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Tygacil | Pfizer Global Pharmaceuticals | Laborex Kenya Eurapharma Ltd | 50mg | 10 | Injection | per vial | KES 69,377.00 |
| Tigecycline | |
|---|---|
| Mode Of Action | irreversibly binds to 30s sub-unit of bacterial ribosomes; blocks recognition step in protein synthesis and causes growth inhibition. |
| Drug Indication | Intra-abdominal infections caused by susceptible bacteria and community-acquired bacterial pneumonia caused by Streptococcus pneumoniae, Haemophilus influenzae, and Legionella pneumophila. |
| Precautions | Cholestasis |
| Contra-Indications | allergy to tetracyclines; foot infections in diabetics |
| Side Effects | The most common side effects: diarrhea, nausea and vomiting. Other side effects: pain at the site of injection, swelling and irritation; increased or decreased heart rate and infections, increased sensitivity to sunlight, permanent discoloration of teeth if used during tooth development, pseudomembranous colitis |
| Dosage | 100mg STAT then 50mg BD x 5 - 14 days |
| Special Information | It is active against some tetracycline, methicillin and vancomycin-resistant microrganisms |
| Pregnancy Category | Category D |
| Pregnancy Category Description | Drugs, which have caused, are suspected to have caused, or may be expected to cause an increased rise in the frequency of malformations or irreversible damage. These drugs may also have adverse pharmacological effects required required |
| Drug Category | DRUGS ACTING ON INFECTIONS |
| Drug Sub-Category | Tetracyclines |
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Tygacil | Pfizer Global Pharmaceuticals | Laborex Kenya Eurapharma Ltd | 50mg | 10 | Injection | per vial | KES 69,377.00 |