dosage;
250 mg every 8 hours, doubled for severe infections; max. 4g daily;
Child over 1 month, 20 mg/kg daily in 3 divided doses,
doubled for severe infections, max. 1 g daily; or 1 month-
Child1 year, 62.5 mg every 8 hours;
1-5 years, 125 mg;
Child over 5 years, 250 mg; doses doubled for severe infections.
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Ceclor | Eli Lilly & Co. | Statim Pharmaceuticals Ltd | 375mg | 10 | Tablet | per tablet | KES 1,049.70 |
| Ceclor | Eli Lilly & Co. | Statim Pharmaceuticals Ltd | 125mg | 75ml | Dry Syrup | per 5ML | KES 629.80 |
| Ceclor | Eli Lilly & Co. | Statim Pharmaceuticals Ltd | 250mg | 75ml | Dry Syrup | per 5ML | KES 1,078.90 |
| Ceclor | Eli Lilly & Co. | Statim Pharmaceuticals Ltd | 375mg | 50ml | Dry Syrup | per 5ML | KES 1,078.90 |
| Halocef | Aristo Pharmaceuticals Ltd. | British Pharmaceuticals Ltd | 125mg | 100ml | Suspension | per 5ML | KES 520.00 |
| Labclor | Laboratory & Allied Ltd. | Laboratory & Allied Ltd | 250mg | 10 | Capsule | per capsule | KES 295.00 |
| Labclor | Laboratory & Allied Ltd. | Laboratory & Allied Ltd | 500mg | 10 | Capsule | per capsule | KES 295.00 |
| Vercef | Ranbaxy | 375mg | 10s | tablet | per tab | KES 752 |
| Mode Of Action | Inhibits synthesis of bacterial cell wall, causing cell death, hence bactericidal. required. |
|---|---|
| Drug Indication | Respiratory tract infections, otitis media, skin and tissues infections and other infections caused by susceptible micro-organisms. |
| Precautions | Impaired renal functions, penicillin cross sensitivity |
| Contra-Indications | Sensitivity to cephalosporins. |
| Side Effects | Diarrhoea and rarely antibiotic-associated colitis, nausea and vomiting, abdominal discomfort, headache; allergic reactions including rashes, pruritus, urticaria, serum sickness-like reactions with rashes, fever, arthralgia and anaphylaxis; Stevens-Johnson syndrome, toxic epidermal necrolysis; disturbances in liver enzymes, transient hepatitis and cholestatic jaundice; other side-effects reported include eosinophilia and blood disorders (including thrombocytopenia, leucopenia, agranulocytosis, a |
| Dosage | 250 mg every 8 hours, doubled for severe infections; max. 4g daily; child over 1 month, 20 mg/kg daily in 3 divided doses, doubled for severe infections, max. 1 g daily; or 1 month-1 year, 62.5 mg every 8 hours; 1-5 years, 125 mg; over 5 years, 250 mg; doses doubled for severe infections. |
| Pregnancy Category | Category B1 |
| Pregnancy Category Description | Drugs which have been taken by only a small number of pregnant women and women of child-bearing age with no any established rise in the frequency of malformations or other direct or indirect detrimental effects on the foetus having been noted. Studies in animals have not shown evidence of an increased occurrence of foetal damage. |
| Drug Category | DRUGS ACTING ON INFECTIONS |
| Drug Sub-Category | Cephalosporins |