Dosage;
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Kefnir | Glenmark | Galaxy Pharmaceuticals Ltd | 300mg | 12 | Capsule | per capsule | KES 498.00 |
| Kefnir | Glenmark | Galaxy Pharmaceuticals Ltd | 125mg | 30ml | Suspension | per 5ML | KES 498.00 |
| Kefnir | Glenmark | Galaxy Pharmaceuticals Ltd | 125mg | 60ml | Suspension | per 5ML | KES 775.00 |
| Mode Of Action | Inhibits synthesis of bacterial cell wall, causing cell death, hence bactericidal. required. |
|---|---|
| Drug Indication | Respiratory tract infections, otitis media, skin and tissues infections and other infections caused by susceptible micro-organisms. |
| Precautions | Impaired renal functions, penicillin cross sensitivity; there have been reports of reddish stools in patients given cefdinir with iron supplements. |
| Contra-Indications | Sensitivity to cephalosporins. |
| Side Effects | GI disturbances, vaginal moniliasis and vaginitis, allergic reactions, increased prothrombin time, super-infections, hepatic dysfunctions, Stevens-Johnson syndrome, erythema multiforme, fever, CNS effects. |
| Dosage | Usual oral dose of 600mg daily as a single dose or in two divided doses. Twice daily dosing should be used for pneumonia and skin infections. The dose of cefdinir may need to be reduced in patients with renal impairment. Children from 6 months of age may be given 14mg/kg daily as a single dose or in two divided doses (to a maximum daily dose of 600mg). |
| Special Information | A third generation cephalosporin that is similar to cefixime. In vitro tests show that it is more active than cefixime against S. aureus and E. faecalis but less active against Enterobacteriacea. |
| Pregnancy Category | Category B1 |
| Pregnancy Category Description | Drugs which have been taken by only a small number of pregnant women and women of child-bearing age with no any established rise in the frequency of malformations or other direct or indirect detrimental effects on the foetus having been noted. Studies in animals have not shown evidence of an increased occurrence of foetal damage. |
| Drug Category | DRUGS ACTING ON INFECTIONS |
| Drug Sub-Category | Cephalosporins |