Cefuroxime

Dosage;

By mouth (as cefuroxime axetil), 250mg twice daily in most infections

including mild to moderate lower respiratory-tract infections (e.g. bronchitis);

doubled for more severe lower respiratory-tract infections or if pneumonia suspected.

Urinary-tract infection, 125mg twice daily, doubled in pyelonephritis. Gonorrhoea, 1g as a single dose.

Child over 3 months, 125mg twice daily, if necessary doubled in child over 2 years with otitis media.

Lyme disease, adult and child over 12 years, 500mg twice daily for 14-21 days

(for 28 days in Lyme arthritis) [unlicensed duration].

By I.M injection or I.V injection or infusion, 750mg every 6-8 hours;

1.5g every 6-8 hours in severe infections; single doses over 750mg I.V route only.

Child usual dose 60 mg/kg daily (range 30-100mg/kg daily) in 3-4 divided doses

(2-3 divided doses in neonates).

Gonorrhoea, 1.5g as a single dose by intramuscular injection (divided between 2 sites).

Surgical prophylaxis, 1.5g by intravenous injection at induction;

up to 3 further doses of 750mg may be given by intramuscular or intravenous injection

every 8 hours for high-risk procedures. Meningitis, 3g intravenously every 8 hours; C

hild, 200-240 mg/kg daily (in 3-4 divided doses) reduced to 100 mg/kg daily after 3 days

or on clinical improvement; neonate, 100mg/kg daily reduced to 50mg/kg daily.

Cefuroxime Brands

Brand Name Manufacturer Name Distributor Drug Strength Packaging Formulation Formulation Strength Price
Altacef Glenmark Galaxy Pharmaceuticals Ltd 250mg 10 Tablet per tablet KES 442.00
Altacef Glenmark Galaxy Pharmaceuticals Ltd 500mg 10 Tablet per tablet KES 900.00
Altacef Glenmark Galaxy Pharmaceuticals Ltd 125mg 50ml Suspension per 5ML KES 394.00
Axacef Sanofi Aventis Surgipharm Ltd 250mg 10 Tablet per tablet KES 415.00
Axacef Sanofi Aventis Surgipharm Ltd 250mg 14 Tablet per tablet KES 493.00
Axacef Sanofi Aventis Surgipharm Ltd 500mg 10 Tablet per tablet KES 800.00
Axacef Sanofi Aventis Surgipharm Ltd 500mg 14 Tablet per tablet KES 750.00
Bcef Bharat Biotech International Ltd Pharma Specialities Ltd. 250mg 10 Tablet per tablet KES 480.00
Bcef Bharat Biotech International Ltd Pharma Specialities Ltd. 500mg 10 Tablet per tablet KES 600.00
Bcef Bharat Biotech International Ltd Pharma Specialities Ltd. 125mg 50ml Suspension per 5ML KES 260.00
Cefact Cipla Ltd. Surgipharm Ltd 500mg 10 Tablet per tablet KES 1,063.00
Cefact Cipla Ltd. Surgipharm Ltd 750mg 15ml Injection per vial KES 402.00
Cefakind Mankind Pharma Limited Pharma Specialities Ltd. 500mg 10 Tablet per tablet KES 530.00
Cefasyn Cipla Ltd. Surgipharm Ltd 500mg 10 Tablet per tablet KES 750.00
Cefasyn Cipla Ltd. Surgipharm Ltd 750mg 15ml Injection per vial KES 380.00
Cefeal Questa Care Inc. Simba Pharmaceutical Ltd. 125mg 50ml Suspension per 5ML KES 450.00
Cefogen Cadila Pharmaceuticals Ltd. Cadila Pharmaceuticals (EA) 750mg 1 Injection per vial KES 310.00
Cefotil Square Pharmaceuticals Ltd ACE Pharmaceuticals Ltd 250mg 20 Tablet per tablet KES 750.00
Cefotil Square Pharmaceuticals Ltd ACE Pharmaceuticals Ltd 500mg 10 Tablet per tablet KES 650.00
Cefotil Square Pharmaceuticals Ltd ACE Pharmaceuticals Ltd 125mg 70ml Suspension per 5ML KES 380.00
Cefotil Square Pharmaceuticals Ltd ACE Pharmaceuticals Ltd 750mg 1 Injection per vial KES 300.00
Cefoxim Biochem Sai Pharmaceuticals Ltd. 250mg 10 Tablet per tablet KES 510.00
Cefoxim Biochem Sai Pharmaceuticals Ltd. 500mg 10 Tablet per tablet KES 765.00
Cefoxim Biochem Sai Pharmaceuticals Ltd. 750mg 1 Injection per vial KES 263.00
Ceftyl Dafra Phama Harley's Limited 500mg 10 Tablet per tablet KES 1,015.00
Cefuken Sance Laboratories Ltd Pharmaken Ltd 500mg 10 Tablet per tablet KES 1,125.00
Cefuken Sance Laboratories Ltd Pharmaken Ltd 125mg 50ml Suspension per 5ML KES 565.00
Cefuxime Aurobindo Pharma Ltd. Simba Pharmaceutical Ltd. 250mg 10 Tablet per tablet KES 350.00
Cefuxime Aurobindo Pharma Ltd. Simba Pharmaceutical Ltd. 500mg 10 Tablet per tablet KES 520.00
Cefuxime Aurobindo Pharma Ltd. Simba Pharmaceutical Ltd. 750mg 1 Injection per vial KES 230.00
Cefuzime Gulf Pharmaceuticals (See also Julphar) Goodman Agencies Ltd 250mg 10 Tablet per tablet KES 800.00
Cefuzime Gulf Pharmaceuticals (See also Julphar) Goodman Agencies Ltd 500mg 10 Tablet per tablet KES 1,250.00
Cefuzime Gulf Pharmaceuticals (See also Julphar) Goodman Agencies Ltd 125mg 50ml Suspension per 5ML KES 700.00
Celzar Cachet Pharmaceuticals PVT Ltd Galaxy Pharmaceuticals Ltd 500mg 10 Tablet per tablet KES 550.00
Celzar Cachet Pharmaceuticals PVT Ltd Galaxy Pharmaceuticals Ltd 750mg 15ml Injection per vial KES 402.00
Celzar Cachet Pharmaceuticals PVT Ltd Galaxy Pharmaceuticals Ltd 150mg 50ml Syrup per 5ML KES 350.00
C-tri T Emcure Pharmaceuticals Limited Syner-Medica (K) Ltd 250mg 10 Tablet per tablet KES 300.00
C-tri T Emcure Pharmaceuticals Limited Syner-Medica (K) Ltd 500mg 10 Tablet per tablet KES 330.00
Evorox Pharmevo Pharmaceuticals Ltd Harley's Limited 750mg 1 Injection per vial KES 319.00
Evorox Pharmevo Pharmaceuticals Ltd Harley's Limited 125mg 50ml Suspension per 5ML KES 479.00
Forcef Aristo Pharmaceuticals Ltd. British Pharmaceuticals Ltd 250mg 40 Tablet per tablet KES 1,600.00
Forcef Aristo Pharmaceuticals Ltd. British Pharmaceuticals Ltd 500mg 10 Tablet per tablet KES 550.00
Forcef Aristo Pharmaceuticals Ltd. British Pharmaceuticals Ltd 750mg 1 Injection per vial KES 360.00
Furocef Renata Limited Unisel Pharma (K) Ltd. 250mg 16 Tablet per tablet KES 390.00
Furocef Renata Limited Unisel Pharma (K) Ltd. 500mg 12 Tablet per tablet KES 450.00
Furotil Healthcare Pharmaceuticals Crown Healthcare 250mg 10 Tablet per tablet KES 365.00
Furotil Healthcare Pharmaceuticals Crown Healthcare 500mg 10 Tablet per tablet KES 640.00
Infrid Medicraft Pharmaceuticals Ltd Kulal International Ltd. 750mg 1 Injection per vial KES 148.00
Kefax Prisma Pharmaceuticals Ltd. Galaxy Pharmaceuticals Ltd 250mg 10 Tablet per tablet KES 510.00
Kefax Prisma Pharmaceuticals Ltd. Galaxy Pharmaceuticals Ltd 500mg 10 Tablet per tablet KES 850.00
Kefstar Wockhardt International Pharma Specialities Ltd. 250mg 10 Tablet per tablet KES 494.00
Kefstar Wockhardt International Pharma Specialities Ltd. 500mg 10 Tablet per tablet KES 790.00
Kefstar Wockhardt International Pharma Specialities Ltd. 125mg 50ml Suspension per 5ML KES 482.00
Kefstar Wockhardt International Pharma Specialities Ltd. 750mg 1 Injection per vial KES 248.00
Kefrox CCL Pharma Harley's Limited 500mg 10 Tablet per tablet KES 778.00
Kefrox CCL Pharma Harley's Limited 125mg 50ml Suspension per 5ML KES 449.00
Kefrox CCL Pharma Harley's Limited 250mg 50ml Suspension per 5ML KES 603.00
Kefrox CCL Pharma Harley's Limited 750mg 1 Injection per vial KES 200.00
Kefurox Flamingo Pharmaceuticals Ltd. Harley's Limited 250mg 10 Tablet per tablet KES 160.00
Kefurox Flamingo Pharmaceuticals Ltd. Harley's Limited 500mg 10 Tablet per tablet KES 525.00
Kefurox Flamingo Pharmaceuticals Ltd. Harley's Limited 750mg 1 Injection per vial KES 90.00
Kilbac Incepta Pharma Radiance Pharmaceuticals Limited 125mg 70ml Suspension per 5ML KES 400.00
Medcefur Comed Chemicals Europa Healthcare Ltd. 250mg 10 Tablet per tablet KES 645.00
Medcefur Comed Chemicals Europa Healthcare Ltd. 500mg 10 Tablet per tablet KES 1,105.00
Milcef Comed Chemicals Europa Healthcare Ltd. 250mg 10 Tablet per tablet KES 890.00
Milcef Comed Chemicals Europa Healthcare Ltd. 500mg 10 Tablet per tablet KES 960.00
Proximexa GlaxoSmithkline GlaxoSmithKline 250mg 10 Tablet per tablet KES 816.80
Proximexa GlaxoSmithkline GlaxoSmithKline 500mg 10 Tablet per tablet KES 1,469.00
Proximexa GlaxoSmithkline GlaxoSmithKline 125mg 50ml Suspension per 5ML KES 567.60
Proximexa GlaxoSmithkline GlaxoSmithKline 250mg 50ml Suspension per 5ML KES 887.30
Pulmocef Micro - Labs Limited Pharma Specialities Ltd. 250mg 10 Tablet per tablet KES 371.00
Pulmocef Micro - Labs Limited Pharma Specialities Ltd. 500mg 10 Tablet per tablet KES 695.00
Pulmocef Micro - Labs Limited Pharma Specialities Ltd. 750mg 1 Injection per vial KES 333.95
Roxicef Sanofi Aventis Laborex Kenya Eurapharma Ltd 750mg 1 Injection per vial KES 316.00
Roxicef Sanofi Aventis Laborex Kenya Eurapharma Ltd 750mg 10 Injection per vial KES 1,871.00
Rufex Global Pharma Healthcare Pvt. Ltd Medox Pharmaceuticals Ltd. 250mg 10 Tablet per tablet KES 710.00
Rufex Global Pharma Healthcare Pvt. Ltd Medox Pharmaceuticals Ltd. 500mg 10 Tablet per tablet KES 1,215.00
Rufex Global Pharma Healthcare Pvt. Ltd Medox Pharmaceuticals Ltd. 125mg 60ml Suspension per 5ML KES 520.00
Sanfurox Bliss GVS Pharma Ltd (See also GVS) Pan Pharmaceuticals Ltd 750mg 1 Injection per vial KES 235.00
Sefur Opsonin Pharma Radiance Pharmaceuticals Limited 125mg 70ml Suspension per 5ML KES 470.00
Sefur Opsonin Pharma Radiance Pharmaceuticals Limited 750mg 1 Injection per vial KES 280.00
Spizef Orchid Healthcare Sunpar Pharmaceuticals Ltd. 250mg 10 Tablet per tablet KES 625.00
Spizef Orchid Healthcare Sunpar Pharmaceuticals Ltd. 500mg 10 Tablet per tablet KES 875.00
Spizef Orchid Healthcare Sunpar Pharmaceuticals Ltd. 750mg 1 Injection per vial KES 240.00
Synercef Synermed Pharmaceuticals Ltd Saicare Enterprises Ltd. 250mg 10 Tablet per tablet KES 300.00
Synercef Synermed Pharmaceuticals Ltd Saicare Enterprises Ltd. 500mg 10 Tablet per tablet KES 330.00
Synercef Synermed Pharmaceuticals Ltd Saicare Enterprises Ltd. 125mg 50ml Suspension per 5ML KES 340.00
Synercef Synermed Pharmaceuticals Ltd Saicare Enterprises Ltd. 125mg 100ml Suspension per 5ML KES 500.00
Ximecor Coral Laboratories Ltd Signature Healthcare Limited 500mg 10 Tablet per tablet KES 850.00
Zifora Biopharm Group Maxim Pharmaceuticals Ltd 250mg 10 Tablet per tablet KES 250.00
Zifora Biopharm Group Maxim Pharmaceuticals Ltd 500mg 10 Tablet per tablet KES 300.00
Zinacef GlaxoSmithkline GlaxoSmithKline 750mg 5 Injection per vial KES 2,420.90
Zinnat GlaxoSmithkline GlaxoSmithKline 250mg 10 Tablet per tablet KES 1,139.90
Zinnat GlaxoSmithkline GlaxoSmithKline 500mg 10 Tablet per tablet KES 2,091.90
Zinnat GlaxoSmithkline GlaxoSmithKline 125mg 50ml Suspension per 5ML KES 698.10
Zinnat GlaxoSmithkline GlaxoSmithKline 125mg 100ml Suspension per 5ML KES 1,222.20
Zinnat GlaxoSmithkline GlaxoSmithKline 250mg 50ml Suspension per 5ML KES 1,222.20
Zolidon Cosmos Limited. Cosmos Limited 250mg 10 Tablet per tablet KES 600.00
Zolidon Cosmos Limited. Cosmos Limited 500mg 10 Tablet per tablet KES 810.00
Zolidon Cosmos Limited. Cosmos Limited 125mg 50ml Suspension per 5ML KES 420.00
Zolidon Cosmos Limited. Cosmos Limited 125mg 70ml Suspension per 5ML KES 450.00
Zolidon Cosmos Limited. Cosmos Limited 250mg 50ml Suspension per 5ML KES 600.00

Cefuroxime more info

Mode Of Action

Inhibits synthesis of bacterial cell wall, causing cell death, hence bactericidal. required.

Drug Indication Septicaemia, meningitis in neonates and infants, peri-operative infections prophylaxis, UTI, RTI, bone, joints, skin and soft tissue infections, N. gonorrhoea and H. influenza.
Precautions Penicillin sensitivity, pregnancy, impaired renal function.
Contra-Indications Hypersensitivity reactions, penicillin cross-sensitivity.
Side Effects GI disturbances, allergic reactions, blood dyscrasia, severe headaches, glossitis, pain at I.M injection site, pseudomembranous colitis, oedema, genital tract mycosis and oliguria.
Dosage Dose: By mouth (as cefuroxime axetil), 250mg twice daily in most infections including mild to moderate lower respiratory-tract infections (e.g. bronchitis); doubled for more severe lower respiratory-tract infections or if pneumonia suspected.Urinary-tract infection, 125mg twice daily, doubled in pyelonephritis. Gonorrhoea, 1g as a single dose. Child over 3 months, 125mg twice daily, if necessary doubled in child over 2 years with otitis media. Lyme disease, adult and child over 12 years, 500mg twice daily for 14-21 days (for 28 days in Lyme arthritis) [unlicensed duration]. By I.M injection or I.V injection or infusion, 750mg every 6-8 hours; 1.5g every 6-8 hours in severe infections; single doses over 750mg I.V route only.Child usual dose 60 mg/kg daily (range 30-100mg/kg daily) in 3-4 divided doses (2-3 divided doses in neonates). Gonorrhoea, 1.5g as a single dose by intramuscular injection (divided between 2 sites).Surgical prophylaxis, 1.5g by intravenous injection at induction; up to 3 further doses of 750mg may be given by intramuscular or intravenous injection every 8 hours for high-risk procedures. Meningitis, 3g intravenously every 8 hours; child, 200-240 mg/kg daily (in 3-4 divided doses) reduced to 100 mg/kg daily after 3 days or on clinical improvement; neonate, 100mg/kg daily reduced to 50mg/kg daily.
Pregnancy Category Category B:
Pregnancy Category Description Drugs which have been taken by only a small number of pregnant women and women of child-bearing age with no any established rise in the frequency of malformations or other direct or indirect detrimental effects on the foetus having been noted. Categorized further into:
Drug Category DRUGS ACTING ON INFECTIONS
Drug Sub-Category Cephalosporins