Drug List Home Antibacterial Sensitivity Chart

Ertapenem

Ertapenem Dosage

Dosing: Adult I.M., I.V.: 1 g/day; duration of total antibiotic treatment: 10-14 days

Note: I.V. therapy may be administered for up to 14 days; I.M. for up to 7 days

Community-acquired pneumonia and complicated urinary tract infections (including pyelonephritis):

I.M., I.V.: 1 g/day; duration of total antibiotic treatment: 10-14 days

(Note: Duration includes possible switch to appropriate oral therapy after at least 3 days of parenteral treatment,

once clinical improvement demonstrated.)

Intra-abdominal infection: I.M., I.V.: 1 g/day for 5-14 days;

Note: 2010 IDSA guidelines recommend a treatment duration of 4-7 days

(provided source controlled) for community-acquired, mild-to-moderate IAI

Pelvic infections (acute): I.M., I.V.: 1 g/day for 3-10 days

Prophylaxis of surgical site following colorectal surgery: I.V.: 1 g given 1 hour preoperatively

Skin and skin structure infections (including diabetic foot infections): I.M., I.V.: 1 g/day for 7-14 days

Dosing: Pediatric

Note: I.V. therapy may be administered for up to 14 days; I.M. therapy for up to 7 days

Children 3 months to 12 years:

Community-acquired pneumonia and complicated urinary tract infections (including pyelonephritis):

I.M., I.V.: 15 mg/kg twice daily (maximum: 1 g/day); duration of total antibiotic treatment: 10-14 days

(Note: Duration includes possible switch to appropriate oral therapy after at least 3 days of parenteral treatment,

once clinical improvement demonstrated.)

Intra-abdominal infection: I.M., I.V.: 15 mg/kg twice daily (maximum: 1 g/day) for 5-14 days

Pelvic infections (acute): I.M., I.V.: 15 mg/kg twice daily (maximum: 1 g/day) for 3-10 days

Skin and skin structure infections: I.M., I.V.: 15 mg/kg twice daily (maximum: 1 g/day) for 7-14 days

Children ≥13 years: Refer to adult dosing.

Dosing: Geriatric

Refer to adult dosing.

Dosing: Renal Impairment

Children: No data available for pediatric patients with renal insufficiency.

Adults:

Clcr >30 mL/minute/1.73 m2: No adjustment required

Clcr ≤30 mL/minute/1.73 m2 and ESRD: 500 mg/day

Hemodialysis: When the daily dose is given within 6 hours prior to hemodialysis, a supplementary dose of 150 mg is required following hemodialysis

Ertapenem Brands