Adult dose: Severe infections 1-4 million units IV every 4-6 hours.
Meningitis: 4 million units IV every 4 hours.
Neurosyphilis: 18-24 million units/day IV in divided doses for 10-14 days.
Paediatric dose: 50000-100000 units/kg/day IV divided every 4-6 hours.
Benzyl Penicillin Brands
| Brand | Manufacturer | Strength | Formulation | Price |
|---|---|---|---|---|
| Crystalline Penicillin | Laboratory & Allied | 1 Mega Unit | Powder for Injection | KES POR |
| Crystalline Penicillin | Laboratory & Allied | 5 Mega Units | Powder for Injection | KES POR |
| Benzyl Penicillin More action | |
|---|---|
| Mode Of Action | Inhibits bacterial cell wall synthesis causing bacterial cell death. |
| Drug Indication | Streptococcal, pneumococcal and meningococcal infections, syphilis, neurosyphilis, endocarditis, tetanus, gas gangrene and actinomycosis. |
| Precautions | Penicillin allergy, renal impairment, monitor electrolytes with high doses. |
| Contra-Indications | Hypersensitivity to penicillins. |
| Side Effects | Rash, injection site pain, diarrhoea, nausea, anaphylaxis, seizures with excessive doses. |
| Dosage | Adults: 1-4 million units IV every 4-6 hours. Children: 50000-400000 units/kg/day IV depending on indication. |
| Pregnancy Category | Category A. |
| Drug Category | DRUGS ACTING ON INFECTIONS |
| Drug Sub-Category | Penicillins |