Dosage ; 1 capsule daily
(dose form not appropriate for children or in renal impairment
Combinations ; - see below
| Fenofibrate More info | |
|---|---|
| Mode Of Action | Drugs that decrease serum triglycerides and very low-density lipoprotein (VLDL) cholesterol and increase high-density lipoprotein (HDL) |
| Drug Indication | Primary hyperlipidaemia type Iia, Iib, III, IV and V; secondary hyperlipidaemia not responsive to other measures. |
| Precautions | Correct hypothyroidism before initiating treatment. LFTs recommended every 3 months for first year (discontinue treatment if significantly raised). |
| Contra-Indications | Gall bladder disease; pancreatitis (unless due to severe hypertriglyceridaemia); photosensitivity to ketoprofen. |
| Side Effects | Gastro-intestinal disturbances, anorexia; less commonly cholestasis, weight gain, dizziness, headache, fatigue, drowsiness, renal impairment, raised serum creatinine (unrelated to renal impairment), erectile dysfunction, myotoxicity (with myasthenia or myalgia)special risk in renal impairment, urticaria, pruritus, photosensitivity reactions; very rarely gallstones, hypoglycaemia, anaemia, leucopenia, thrombocytopenia, increased platelet count, alopecia, Stevens-Johnson syndrome, and toxic epide |
| Dosage | 1 capsule daily (dose form not appropriate for children or in renal impairment |
| Pregnancy Category | Category C |
| Pregnancy Category Description | Drugs which, owing to their pharmacological effects, or may be suspected of causing detrimental effects on human foetus or neonates without causing malfunctions. These effects may be reversible |
| Drug Category | DRUGS ACTI NG ON THE CARDIO-VASCULAR SYSTEM |
| Drug Sub-Category | Drugs for dyslipidaemia |