Dosage ; Adult & elderly 5 mg in the evening, before retiring.
Dose can be increased to 10 mg following a 1-month clinical assessment (Max: 10 mg/day).
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Aricept | Pfizer Global Pharmaceuticals | Surgipharm Ltd | 5mg | 28 | Tablet | per tablet | KES 2,733.00 |
| Aricept | Pfizer Global Pharmaceuticals | Surgipharm Ltd | 10mg | 28 | Tablet | per tablet | KES 3,613.00 |
| Donecept | ATCO Laboratories (Pvt) Ltd | Globe Pharmacy Ltd., | 5mg | 30 | Tablet | per tablet | KES 1,069.20 |
| Donecept | Globe Pharmacy Ltd., | Globe Pharmacy Ltd., | 5mg | 30 | Tablet | per tablet | KES 1,069.20 |
|
Donepezil More info |
|
|---|---|
| Mode Of Action | Donepezil is a cholinesterase inhibitor that increases the levels of acetylcholine |
| Drug Indication | Symptomatic treatment of mild to moderately severe Alzheimer's dementia |
| Contra-Indications | Pregnancy, children |
| Side Effects | Diarrhoea, muscle cramps, fatigue, nausea and vomiting, insomnia, common cold, anorexia, psychiatric disoders, dizziness, syncope, rash, pruritus, urinary incontinence, headache fatigue, GI disorders. |
| Dosage | Adult & elderly 5 mg in the evening, before retiring. Dose can be increased to 10 mg following a 1-month clinical assessment (Max: 10 mg/day). |
| Drug Category | DRUGS ACTING ON CNS |
| Drug Sub-Category | Anticholinesterases
Dosing: Adult Alzheimer's dementia: Oral: Mild-to-moderate: Initial: 5 mg once daily; may increase to 10 mg once daily after 4-6 weeks; effective dosage range in clinical studies: 5-10 mg/day Moderate-to-severe: Initial: 5 mg once daily; may increase to 10 mg once daily after 4-6 weeks; may increase further to 23 mg once daily after ≥3 months; effective dosage range in clinical studies: 10-23 mg/day Dosing: Geriatric Refer to adult dosing. Note: The Canadian labeling recommends a maximum dose of 5 mg once daily in elderly women of low body weight. |