Dosage ; 1mg daily increased gradually to 5-15mg in 3-4 divided doses.
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Benzhexol | Cosmos Limited. | Cosmos Limited | 5mg | 100 | Tablet | per tablet | KES 165.00 |
| Benzhexol | Laboratory & Allied Ltd. | Laboratory & Allied Ltd | 5mg | 100 | Tablet | per tablet | KES 120.00 |
| Benzhexol | Laboratory & Allied Ltd. | Laboratory & Allied Ltd | 5mg | 1000 | Tablet | per tablet | KES 650.00 |
| Benzhexol | Remedica Ltd. | Twokay Chemicals Ltd | 2mg | 100 | Tablet | per tablet | KES 450.00 |
| Parkin | Prism Life Sciences | Galaxy Pharmaceuticals Ltd | 5mg | 100 | Tablet | per tablet | KES 125.00 |
| Artane | 5mg | 100s | Tablet | per tablet | KES 125.00 |
|
Benzhexol More info |
|
|---|---|
| Mode Of Action | Benzhexol is thought to act by partially blocking central cholinergic receptors, thus helping to balance cholinergic and dopaminergic activity in the basal ganglia. This results in a decrease in salivation and relaxation of the smooth muscles. |
| Drug Indication | Parkinsonism, drug-induced extrapyramidal symptoms. |
| Precautions | Elderly, GI or GU obstruction, glaucoma, hepatic impairment, renal impairment, hypertension. |
| Contra-Indications | Tardive dyskinesia, cardiac arrhythmias, myasthenia gravis, urinary retention, history of sensitivity to benzhexol and related compounds. |
| Side Effects | Anti-muscarinic side effects: dry mouth, blurred vision, urinary retention, GI disturbances, nervousness, allergic reactions, drowsiness, psychiatric disorders, increased intraocular pressure, glaucoma. |
| Dosage | 1mg daily increased gradually to 5-15mg in 3-4 divided doses. |
| Pregnancy Category | Category B1 |
| Pregnancy Category Description | Drugs which have been taken by only a small number of pregnant women and women of child-bearing age with no any established rise in the frequency of malformations or other direct or indirect detrimental effects on the foetus having been noted. Studies in animals have not shown evidence of an increased occurrence of foetal damage. |
| Drug Category | DRUGS ACTING ON CNS |
| Drug Sub-Category | Rigidity and tremor controllers |