Dosage; Usual; Oral: 320 mg once daily for 5- 10 days
Acute exacerbations of chronic bronchitis: Oral: 320 mg once daily for 5 days
Community-acquired pneumonia (mild-to-moderate): Oral: 320 mg once daily for 5 or 7 days
(decision to use 5- or 7-day regimen should be guided by initial sputum culture;
7 days are recommended for MDRSP, Klebsiella, or M. catarrhalis infection)
Sinusitis (unlabeled use): Oral: 320 mg once daily for 10 days
Gemifloxacin Brands
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Actigem | Ferozsons | 7s | 320mg | KES 750 | |||
| Gemiflox | Popular Pharmaceuticals Ltd | Omaera Pharmaceuticals Ltd | 10s | 320mg | KES 938 |
Gemifloxacin more info
| Mode Of Action | interferes with bacterial DNA synthesis by inhibiting topoisomerase II (DNA gyrase) and topoisomerase IV. |
|---|---|
| Drug Indication | ENT, UTI, RTI, skin and soft tissues, bone, joint, GI, intra-abdominal, pelvic and severe infections, gonorrhoea. |
| Precautions | Quinolones should be used with caution in children with a history of epilepsy or conditions that predispose to seizures, in G6PD deficiency, myasthenia gravis (risk of exacerbation). Exposure to excessive sunlight should be avoided (discontinue if photosensitivity occurs). Quinolones may induce convulsions in patients with or without a history of convulsions; taking NSAIDs at the same time may also induce them. May cause arthropathy in the weight-bearing joints of immature animals and are therefore generally not recommended in children and growing adolescents. However, the significance of this effect in humans is uncertain and in some specific circumstances short-term use of a quinolone in children is justified. Should be avoid in pregnancy and lactation. |
| Contra-Indications | History of tendon disorders related to quinolone use, documented hypersensitivity. |
| Dosage | 320mg OD for 5-7 days |
| Pregnancy Category | Category B3 |
| Pregnancy Category Description | Drugs which have been taken by only a small number of pregnant women and women of child-bearing age with no any established rise in the frequency of malformations or other direct or indirect detrimental effects on the foetus having been noted. Studies in animals show evidence of an increased occurrence of foetal damage, the significance of which is uncertain in human |
| Drug Category | DRUGS ACTING ON INFECTIONS |
| Drug Sub-Category | Fluoroquinolones |
Moxifloxacin more information