Ofloxacin / Dexamethasone
Ofloxacin / Ornidazole
Ofloxacin eye drops
| Ofloxacin / Dexamethasone |
|---|
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Oflodex | Helix Pharma (PVT) Ltd. | Globe Pharmacy Ltd., | 14 | Tablet | per tablet | KES 420 | |
| Oflodex | Helix Pharma (PVT) Ltd. | Globe Pharmacy Ltd., | 0.5mg/3mg | 5ml | Drops | KES 174.90 | |
| Oflodex | Globe Pharmacy Ltd., | Globe Pharmacy Ltd., | 0.5mg/3mg | 5ml | Drops | KES 192.00 |
| Ofloxacin / Ornidazole | |
|---|---|
| MOA | interferes with bacterial DNA synthesis by inhibiting topoisomerase II (DNA gyrase) and topoisomerase IV. |
| Indication | Infections by Gram+ve and -ve aerobes and anaerobes along with anaerobes and protozoa. These may include: Intra-abdominal infections; diarrhoea of mixed bacterial and protozoal origin; surgical prophylaxis; surgical wound infections; dental infections; respiratory tract infections like lung abscess, aspiration pneumonia, and bronchiectasis; cellulitis, breast and other cutaneous abscesses, gangrene, diabetic and decubitus ulcers. |
| Precautions | suspected CNS disorders e.g. cerebral arteriosclerosis, epilepsy, multiple sclerosis and other factors known or suspected which predispose to seizures. In renal dysfunction, and in those hypersensitive to quinolones, NSAIDS, antacids, haematinics and anticoagulants, muscle relaxants. |
| Contra-Indications | Pregnancy, lactation, cerebral convulsive disorders, children. |
| Side Effects | Allergic reactions, GI disturbances, muscular and joint pains, blood dyscrasias, CNS effects, muscular co-ordination disturbances, visual and sensory disturbances, hallucinations, convulsions, psychotic reactions. For injection, decreased BP especially by rapid infusion. |
| Dosage | 1 tab BD for 5 to 10 days |
| Pregnancy Category | Category B3 |
| Pregnancy Category Description | Drugs which have been taken by only a small number of pregnant women and women of child-bearing age with no any established rise in the frequency of malformations or other direct or indirect detrimental effects on the foetus having been noted. Studies in animals show evidence of an increased occurrence of foetal damage, the significance of which is uncertain in human |
| Drug Category | DRUGS ACTING ON INFECTIONS |
| Drug Sub-Category | Fluoroquinolones |
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Agiflo-OZ | Agio Pharmaceuticals Limited | Pharma Specialities Ltd. | 200mg/500mg | 50 | Tablet | per tablet | KES 920.00 |
| Combizol | Synermed Pharmaceuticals Ltd | Saicare Enterprises Ltd. | 200mg/500mg | 10 | Tablet | per tablet | KES 400.00 |
| Loobid | Cachet Pharmaceuticals PVT Ltd | Galaxy Pharmaceuticals Ltd | 200mg/500mg | 10 | Tablet | per tablet | KES 330.00 |
| Ojen OZ | Jenburkt Pharmaceuticals Ltd. | Unisel Pharma (K) Ltd. | 200mg/500mg | 100 | Tablet | per tablet | KES 2,870.00 |
| Ornilox | Micro - Labs Limited | Pharma Specialities Lt | 200mg/500mg | 10 | Tablet | per tablet | KES 650.00 |
| Ofloxacin eye drops | |
|---|---|
| Mode Of Action | interferes with bacterial DNA synthesis by inhibiting topoisomerase II (DNA gyrase) and topoisomerase IV. |
| Drug Indication | Bacterial eye infections |
| Drug Sub-Category | Antibacterial ophthalmic drugs |
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Auroflox | Aurolab | Medisel Kenya Ltd | 0.30% | 5ml | eye drops | per ml | KES 278.00 |
| Exocin | Allergan International Ltd. | Radiance Pharmaceuticals Limited | 0.30% | 5ml | eye drops | per ml | KES 648.00 |
| Eyforex | ATCO Laboratories (Pvt) Ltd | Globe Pharmacy Ltd., | 0.30% | 5ml | eye drops | per ml | KES 105.60 |